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For years, large doses of niacin have been used as effective agents to lower cholesterol and triglycerides. With a dosage of 2000-3000 mg niacin per day, a 20-25% reduction in cholesterol is expected. The problem, however, are side effects: blushing, digestive problems and deterioration in diabetes. According to one study, hepatitis occurred in 8 of 15 patients on niacin tablets with slow absorption (this did not occur in one patient on normal niacin). People taking niacin should be supervised by a doctor and should have liver function tests and blood sugar levels, similar to cholesterol and triglyceride levels. Therefore, I recommend using niacin only as a last resort, and only under medical supervision.
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